Why fasting bolsters brain power: Mark Mattson at TEDxJohnsHopkinsUniversity


Mark Mattson is the current Chief of the Laboratory of Neurosciences at the National Institute on Aging. He is also a professor of Neuroscience at The Johns Hopkins University. Mattson is one of the foremost researchers in the area of cellular and molecular mechanisms underlying neurodegenerative disorders such as Alzheimer’s Disease, Parkinson’s Disease, and amyotrophic lateral sclerosis.

In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)


  1. If fasting puts the body under stress and that is what causes all the good changes, the body adapting to the stress of no food, wouldn't that effect wear off as the body becomes used to not receiving food for the longer time? Thus making IF a short term solution for a more active brain and body?

  2. Makes a lot of sense we would have been active in the hunt and gather mode during the more part of evolution and not as lazy as the last few thousand years. We're probably designed to be at our best when hungry and to then activate our brain to be able to best hunt and track down to survive. Hunting is natures exercising and the body at peak performance to survive. This would have been a regular occurrence much more than a modern day in forests etc. Think could possibly the time the body gets rid of and pushes out all the bad stuff. But like time to empty the recycled bins. Ppl won't like fasting on the mass of course because look at them got an obvious society. Should compare this study on the poor countries that can't eat all the time compared to USA.

  3. … and how did you induce the diseases and disorders in the mice? …and where and how did you get the mice that you induced dideases into?
    Peace and infinite Love to All

  4. The science overwhelmingly reveals that the typical diet of three meals a day plus snacks is an unhealthy eating pattern but intermittent fasting is not promoted because of the profit motive. The food and pharmaceutical industries are going to lose money. There is no money to be made on healthy people. So you have to ask yourself a question, is your health more important than the profits of the advertising, food and pharmaceutical industries.

  5. Thank God for people like this gentleman. Pure hard science and no profit motive involved in what he is saying. He needs to get smaller shirts though, as the oversized ones make him look a bit malnourished, wish he isn't.

  6. if eating 3 meals a day change to 2. if eating 2 meals a day chane to 1. if eating one meal a day skip one meal a week. point being no matter where you are you can take small achievable steps to save money, time and improve you health. hard to argue with that.

  7. Hey guys, Can i Fast between 12pm-8pm everyday but still enjoy a coffee in the morning?
    Does it matter how many meals im having? Could i have two BIG meal? Im fairly skinny and dont want to lose weight

  8. I just today finished a four day fast and have never gone this long without food and also, have not felt so good in many years. BTW, I am an epileptic and have noticed a noted decrease in my seizure disorder. This guy couldn't be more right about this topic.

  9. So what causes my hypoglycemia? Sometimes it doesn't bother me and sometimes it does badly. I know it is nutritionally related, but WHICH vitamin or mineral? I upped my greens and quit caffeine and now I rarely get hypoglycemia. So, is it B9 or magnesium? Btw, many people on CR diets also fast, esp. the 8 hour fast.


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